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Fisetin Acts on Multiple Pathways to Reduce the Impact of Age and Disease on CNS Function

It is becoming increasingly clear that neurological diseases are multi-factorial involving disruptions in multiple cellular systems. Thus, while each disease...

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The A.I. Diet.

Some months ago, I participated in a two-week experiment that involved using a smartphone app to track every morsel of...

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Differential Effects of Low- and High-dose Zinc Supplementation on Synaptic Plasticity and Neurogenesis in the Hippocampus of Control and High-fat Diet-fed Mice.

In the present study, we investigated the concentration-dependent effect of zinc (Zn) supplementation on the adult hippocampus in a high-fat...

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Zinc in Alzheimer's Disease: A Meta-Analysis of Serum, Plasma, and Cerebrospinal Fluid Studies.

To evaluate whether zinc levels in serum, plasma, and cerebrospinal fluid are altered in Alzheimer's disease (AD), we performed meta-analyses...

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Ketogenic Diet and Epilepsy: What We Know So Far.

The Ketogenic Diet (KD) is a modality of treatment used since the 1920s as a treatment for intractable epilepsy. It...

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Saturated and trans fats and dementia: a systematic review.

Cognitive disorders of later life are potentially devastating. To estimate the relationship between saturated and trans fat intake and risk...

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The influence of the ketogenic diet on the elemental and biochemical compositions of the hippocampal formation.

A growing body of evidence demonstrates that dietary therapies, mainly the ketogenic diet, may be highly effective in the reduction...

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Impact of Dietary Fats on Brain Functions.

Adequate dietary intake and nutritional status have important effects on brain functions and on brain health. Energy intake and specific...

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Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet.

Low-carbohydrate diets are used to manage obesity, seizure disorders, and malignancies of the central nervous system. These diets create a...

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