Wellness Resources
Glucocorticoids promote breast cancer metastasis
Diversity within or between tumours and metastases (known as intra-patient tumour heterogeneity) that develops during disease progression is a serious...
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Wellness Resources
Flavonoid modulation of GABAA receptors
There has been a resurgence of interest in synthetic and plant-derived flavonoids as modulators of γ-amino butyric acid-A (GABAA) receptor...
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Flavonoids as GABAA receptor ligands: the whole story?
Benzodiazepines are the most widely prescribed class of psychoactive drugs in current therapeutic use, despite the important unwanted side effects...
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Endocrinology of parturition.
The myometrium must remain relatively quiescent during pregnancy to accommodate growth and development of the feto-placental unit, and then must...
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Brexanolone drug/nutrient interactions
List of drugs listed as "monitor closely" when interacting with bebrexanolone (Zulresso):acetaminophen/phenyltoloxamineacrivastinealfentanilalprazolamamobarbitalarbaclofenaripiprazoleasenapinebaclofenbenperidolbenzhydrocodone/acetaminophenbrexpiprazolebrivaracetambrompheniraminebuprenorphinebuprenorphine buccalbuprenorphine subdermal implantbuprenorphine transdermalbuprenorphine, long-acting injectionbuspironebutabarbitalbutalbitalbutorphanolcarbamazepinecarbinoxaminecariprazinecarisoprodolchloral hydratechlordiazepoxidechlorpheniraminechlorpromazinechlorzoxazoneclemastineclobazamclonazepamclonidineclorazepateclozapinecodeinecyclobenzaprinecyproheptadinedantrolenedesfluranedeutetrabenazinedexbrompheniraminedexchlorpheniraminediazepamdimenhydrinatediphenhydraminediphenoxylate hcldosulepindoxylaminedroperidolefavirenzemedastineentacaponeesketamine intranasalestazolameszopicloneethanolethosuximideethotoinezogabinefelbamatefentanylfentanyl...
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Bench-to-bedside: NIMH research leads to brexanolone, first-ever drug specifically for postpartum depression
Approximately 1 in 9 women in the United States experiences symptoms of postpartum depression, according to the Centers for Disease...
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FDA approves first treatment for post-partum depression
The U.S. Food and Drug Administration today approved Zulresso (brexanolone) injection for intravenous (IV) use for the treatment of postpartum...
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Protective effect of 7,3',4'-flavon-3-ol (fisetin) on acetaminophen-induced hepatotoxicity in vitro and in vivo.
BACKGROUND:Acetaminophen (APAP) overdose is a leading cause of drug-induced acute liver failure in clinic. Fisetin (FST) is a phenolic compound...
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Mitigative effects of the bioactive flavonol fisetin on high-fat/high-sucrose induced nonalcoholic fatty liver disease in rats.
BACKGROUND:Worldwide growing rates of obesity are correlated with the rising prevalence of nonalcoholic fatty liver disease (NAFLD) with limited available...
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