HEALTH NEWS

Study Title:

HDL2 Associated With Better Heart Health

Study Abstract

Cholesterol (C) concentrations in the two major subtractions of high-density lipoproteins (HDL2-C and HDL3-C) in sera from both sexes, ages ranging from newborns to adults, were measured by use of a micromethod for combined precipitation-ultracentrifugation. Sera were obtained from 91 boys, 68 girls, 15 healthy men, and 14 women. The HDL2-C concentration was higher in women than in men; the HDL3-C concentration was similar in these two groups. This sexrelated
difference, generally seen in adults, was found to begin at ages 11-15 y. The value of HDL2-C in females increased with age in a stepwise manner, whereas that in
males increased up to ages 6-10 y but tended to decline thereafter. The HDL3-C concentration was higher in the adults than in the children. This micromethod for separating operationally defined HDL subtractions is of value for lipoprotein research in children.

Study Information

Kohtaro Aeayama, Aklyo Mlyao, and Klyohlko Kato.
High-Density Lipoprotein (HDL), HDL2, and HDL3 Cholesterol Concentrations Determined in Serum of Newborns, Infants, Children, Adolescents, and Adults by Use of a Micromethod forCombined Precipitation Ultracentrifugation.
CLINICALCHEMISTRY
1990 January