Berberine Ultra™ is an innovative berberine extract with enhanced bioabsorption. It supports glucose, lipid, and metabolic health and promotes a healthy body composition.*

Advanced Absorption

Berberine Ultra™ contains Berbevis® Berberine Phytosome™, a dramatic advancement in berberine supplementation. Containing berberine sourced from Berberis aristata in a phytosome delivery system, this form of berberine solves the problem of poor bioavailability and bioabsorption that characterizes the standard extract.

Berberine Ultra™ features raw Berberis aristata extract, more soluble than pure berberine. This is combined with pea protein, sunflower lecithin and grape seed extract to create a phospholipid complex with enhanced bioavailability and tolerability. A single 550mg capsule of Berberine Ultra™ shows four times better bioavailability compared to 500mg of Berberine HCL.

What Is Berberine?

Berberine is a plant-derived polyphenol that has been used for centuries in China, India, native North America, and other cultures. This deep yellow colored herb is naturally found in goldenseal, Oregon grape and other plants. Numerous human clinical trials validate its historical traditional use for a vast array of health benefits.*

Berberine provides a wide array of stunning benefits. It works by addressing root issues such as managing inflammation and oxidative stress, supporting microbiome balance, as well as through modulation of important cellular targets like AMPK and key metabolic enzymes.* It is a natural isoquinoline alkaloid, which provides basic nitrogen atoms. This structure affects a great many physiological actions.*

Berberine enhances the activities of beneficial endothelial nitric oxide synthase (eNOS) which supports vascular function. It also modulates cholesterol metabolism in the liver and intestinal tract. Furthermore, berberine has been shown to inhibit the activity of various compounds like NF-kappa B, COX-2, MAPK, and others.*

AMPK Activator

Berberine is an AMPK activator (5’-adenosine monophosphate-activated protein kinase) and is found in cells throughout the body, especially in the hypothalamus, liver, muscle, adipose tissue and pancreas. AMPK is a master regulator of energy metabolism. AMPK activity declines with age and stress.*

AMPK regulates important cellular processes such as glucose, lipid, and protein metabolism. It is needed to make new mitochondria and clean up old, worn-out mitochondria and cell growth. Mitochondria are energy factories inside all internal organs and are at the heart of cellular vitality and aging well.*

Blood Sugar Health

Due to its role with AMPK activation, antioxidant, and nitric oxide modulatory activities, berberine supports healthy blood sugar and insulin metabolism. It also supports heart and blood vessel health and healthy cholesterol function.*

Brain, Gut, and Beyond

Berberine is also used for neuroprotection, mood and cognitive support, gut microbiome balance, intestinal mucosal barrier integrity, metabolic function of the liver, pancreas support, immune system function and recognition of bacteria and rogue cells. It also provides protective support for joint and cartilage health and bone density.*

Dosage

Take 1 capsule, up to 2 times per day with or without food. If you are pregnant or planning to become pregnant do not take berberine. It is also not recommended during breastfeeding.