Wellness Resources Weight Management Supplements help improve leptin hormone communication, reduce food cravings, increase energy, support healthy thyroid function, and improve blood sugar metabolism. They make getting started on a weight loss program easier and can help you get beyond a weight loss plateau.* Nutritional supplements are tools to use in...

Leptin is the single most important hormone that regulates your body weight. It is the boss of thyroid hormone, insulin, growth hormone, and adrenal hormones (like cortisol). Understanding leptin and working in harmony with it opens an entire new world of possibilities to maintain and attain optimal metabolic function. Leptin is known as the fat hormone...

The overall function of thyroid hormone in your body is occurring with permission from the big hormone boss, leptin. Not surprisingly, leptin regulation of bone is even more important than thyroid regulation of bone. We now understand that leptin regulates bone in two primary ways: 1) Leptin signals your subconscious brain (hypothalamus) to turn on...

No simple fix or miracle weight loss pill will ever address the complexity of leptin in your metabolism. Beware of false marketing for any one product making this claim (Many leptin products are out there, all of them riding on our coattails, as we are the original leptin experts). On the other hand, there are many nutrients that beneficially impact...

Stress implies that there is an increased need for energy. Leptin, which is overall in charge of your body's energy spending systems, also regulates your adrenal and nervous system response to stress. When leptin systems work efficiently you have a better ability to tolerate stress, do not feel wired up or exhausted from stress, and do not eat in response...

Leptin orchestrates blood sugar and insulin metabolism through central mechanisms in your nervous system and by communicating to your pancreas to stop insulin production at the end of a meal. When these systems are running smoothly they help you maintain a healthy weight and stay on a healthy weight management program. Key nutrients in Cinnamon Plus™ and...

There are five simple rules that form the core of The Leptin Diet. The quality of the food you eat is of course important. What is interesting about The Leptin Diet is that it is just as important when you eat as what you eat.

A decade ago I recognized the extreme importance of leptin to human health. Leptin is the king of hormones which impacts everything else in your body. My first book on the subject in 2002, Mastering Leptin, was the first translation of highly complex science into readable English for the general public – specifically addressing how to eat to be in harmony...

The fat-hormone leptin must get into your brain in order to activate your metabolism and help protect your brain from inflammation and damage. A new study documents that leptin even protects brain cells from low oxygen states that are related to stroke damage.

When a person gains weight it is typical that leptin levels rise too high in the blood and do not get into the brain – a problem called leptin resistance that is a key force behind overeating and becoming overweight. For the first time researchers show that excessive leptin in the blood upregulates leptin receptors on thyroid cancer cells causing them to...

Your liver plays a central role in the metabolism of any type of calorie. During weight gain your liver is being punched in the nose by inflammatory metabolic flu signals coming from your white adipose tissue (stored fat) and your digestive tract (bacterial imbalance, LPS, Candida, etc.). At the same time, your white adipose tissue is unable to store fat...

In order to really take charge of leptin you have to actively manage it. Think of leptin as the conductor of your orchestra; will you play beautiful music or does your body suffer from out of tune noise?

Curcumin eliminates leptin's effects on hepatic stellate cell activation via interrupting leptin signaling.

Acetyl-L-carnitine supplementation differently influences nutrient partitioning, serum leptin concentration and skeletal muscle mitochondrial respiration in young and old rats.

A High-Protein Diet Induces Sustained Reductions in Appetite, Ad Libitum Caloric Intake, and Body Weight Despite Compensatory Changes in Diurnal Plasma Leptin and Ghrelin Concentrations.

Difference in leptin hormone response to nutritional status in normal adult male albino rats.

Fructose-Induced Leptin Resistance Exacerbates Weight Gain in Response to Subsequent High Fat Feeding

Leptin induces IL-8 expression via leptin receptor, IRS-1, PI3K, Akt cascade and promotion of NF-kappaB/p300 binding in human synovial fibroblasts.