SIRT1 is the primary gene signal involved with the longevity benefits of calorie restriction. SIRT1 affects how your body metabolizes fats. Top supplements that help activate the SIRT1 gene include Pterostilbene, Resveratrol Ultra 500, and Fisetin.*

Autophagy is the process by which your body clears out old cells. Efficiency of autophagy is essential for cell health and cognitive function. Top nutritional support for autophagy includes Brain Protector, Fisetin, Astaxanthin, Turmeric Gold, Berberine Ultra, and Green Tea Extract.

Mitochondria are your cell's engines, critical for energy production. How is your energy level throughout the day and your energy when exercising? Mitochondrial health is of utmost importance to living a healthy, active, and vibrant life. Top mitochondria supplements include PQQ, Super CoQ10 Ubiquinol, and Fisetin.*

Fisetin is a hidden gem in the world of nutrition. Like resveratrol and curcumin, but lesser talked about, fisetin is a super nutrient. Known as a "smart" nutrient that supports cognition.

Consider adding Fisetin to improve memory and cognitive function as well as joint health and even heavy metal detoxification!

The inability of a cell to take out the trash is likely a common theme behind many cancers. Researchers at the Kimmel Cancer Center have shown for the first time how the deactivation of the SIRT1 gene causes trash removal to go on the blink and prostate cancer to kick into gear.

Commonly prescribed medications for ADHD are proving harmful to the brain. Discover the latest research and how you can improve ADHD naturally.

Learn about our newest product - PEA Ultra. It is a lipid that supports the body’s endocannabinoid system to promote healthy stress response, mood, relaxation, and nerve function and more!

We are made to believe that sun exposure is harmful and that failure to wear sunscreen is unsafe and risky. In excess, too much sun can cause blistering sunburns and aging skin. However, sun exposure is important for vitamin D synthesis throughout the body and even cellular energy. Knowing how the skin maintains protection against UV radiation is...

Structural requirements for the flavonoid fisetin in inhibiting fibril formation of amyloid beta protein.

Flavonoid fisetin promotes ERK-dependent long-term potentiation and enhances memory.

Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells.

Modulation of multiple pathways involved in the maintenance of neuronal function during aging by fisetin.

Fisetin Lowers Methylglyoxal Dependent Protein Glycation and Limits the Complications of Diabetes

Suppressive effects of flavonoid fisetin on lipopolysaccharide-induced microglial activation and neurotoxicity.