Leptin orchestrates blood sugar and insulin metabolism through central mechanisms in your nervous system and by communicating to your pancreas to stop insulin production at the end of a meal. When these systems are running smoothly they help you maintain a healthy weight and stay on a healthy weight management program. Key nutrients in Cinnamon Plus™ and...

It is very common that individuals who are overweight have a majority of the symptoms associated with a sluggish thyroid function. This is especially true for those who have a history of yo-yo dieting or have difficulty losing weight by cutting back on calories and trying to exercise more. Leptin is known as the fat-hormone, as it is made in your white...

No simple fix or miracle weight loss pill will ever address the complexity of leptin in your metabolism. Beware of false marketing for any one product making this claim (Many leptin products are out there, all of them riding on our coattails, as we are the original leptin experts). On the other hand, there are many nutrients that beneficially impact...

Leptin orchestrates blood sugar and insulin metabolism through central mechanisms in your nervous system and by communicating to your pancreas to stop insulin production at the end of a meal. When these systems are running smoothly they help you maintain a healthy weight and stay on a healthy weight management program. Key nutrients in Cinnamon Plus™ and...

Extra weight fuels estrogen dominance and stresses insulin function. These factors need to be well managed to maintain optimal female hormone balance and health. There is extensive information on our website regarding weight management, including our groundbreaking information on The Leptin Diet. Below are a few of our most popular options.

Sirtuins are types of proteins that directly impact the SIRT genes, cellular aging, and DNA expression that affect quality aging and longevity. Activation of the sirtuin proteins and SIRT genes are linked with lifespan, cell survival, insulin regulation and neuroprotection. Activation of sirtuins are central regulators of mitochondrial activity, membrane...

A unique strain of mouse was bred to have no insulin receptors on its bone-building osteoblasts, although it had insulin receptors every place else. The mouse became fat. As it aged it grew even fatter and its blood sugar levels shot up and it developed severe insulin resistance. The mouse was treated with osteocalcin and the problems reversed....

A new study of 5,450 postmenopausal women shows double the risk for breast cancer in women with elevated insulin. As I recently reported, this risk goes up further if a postmenopausal woman is also taking estradiol, whether from horse urine or bioidentical.

If you want to live to be over 100 and be healthy then it is worth knowing that common findings are good bone health and no insulin resistance. On the other hand, a new study of men over the age of 70 links their risk of fracture to having the metabolic syndrome (insulin resistance and an expanded waistline.)

There are five simple rules that form the core of The Leptin Diet. The quality of the food you eat is of course important. What is interesting about The Leptin Diet is that it is just as important when you eat as what you eat.

Thyroid medications are the most commonly prescribed drugs in the United States. Hidden deep within the drug literature precautions is startling information about blood sugar risks. Are you aware of this risk?

Your liver plays a central role in the metabolism of any type of calorie. During weight gain your liver is being punched in the nose by inflammatory metabolic flu signals coming from your white adipose tissue (stored fat) and your digestive tract (bacterial imbalance, LPS, Candida, etc.). At the same time, your white adipose tissue is unable to store fat...

Insulin causes hyperthermia by direct inhibition of warm sensitive neurons.

Increased fat accumulation in liver may link insulin resistance with subcutaneous abdominal adipocyte enlargement, visceral adiposity, and hypoadiponectinemia in obese individuals

Autocrine action of adiponectin on human fat cells prevents the release of insulin resistance-inducing factors.

Sedentary lifestyle and its relation to cardiovascular risk factors, insulin resistance and inflammatory profile.

Dietary corosolic acid ameliorates obesity and hepatic steatosis in KK-Ay mice.

Xanthones from Mangosteen Prevent Lipopolysaccharide-Mediated Inflammation and Insulin Resistance in Primary Cultures of Human Adipocytes.