Wellness Resources
Developmental lead neurotoxicity: alterations in brain cholinergic system.
Developing brain has been shown to be susceptible to the neurotoxic effects of lead (Pb). Our earlier studies (Reddy GR,...
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Cholinergic Crisis.
Cholinergic crisis is a clinical condition that develops as a result of overstimulation of nicotinic and muscarinic receptors at the...
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Increased susceptibility to methotrexate-induced toxicity in nonalcoholic steatohepatitis.
Hepatic drug metabolizing enzymes and transporters play a crucial role in determining the fate of drugs, and alterations in liver...
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Dietary Neurotransmitters: A Narrative Review on Current Knowledge.
Foods are natural sources of substances that may exert crucial effects on the nervous system in humans. Some of these...
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USDA Database for the Choline Content of Common Foods Release Two.
Research has shown that choline is important for the synthesis of phospholipids in cell membranes, methyl metabolism, acetylcholine synthesis, and...
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The Obesity-Impulsivity Axis: Potential Metabolic Interventions in Chronic Psychiatric Patients.
Pathological impulsivity is encountered in a broad range of psychiatric conditions and is thought to be a risk factor for...
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Bidirectional Neural Interaction Between Central Dopaminergic and Gut Lesions in Parkinson's Disease Models.
The exact mechanism of gut dysfunction in Parkinson's disease and, conversely, the role of gut pathology in brain dopaminergic degeneration...
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Acetylcholine-producing T cells in the intestine regulate antimicrobial peptide expression and microbial diversity.
The cholinergic anti-inflammatory pathway reduces systemic tumor necrosis factor (TNF) via acetylcholine-producing memory T cells in the spleen. These choline...
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Deletion of choline acetyltransferase in enteric neurons results in postnatal intestinal dysmotility and dysbiosis.
Acetylcholine (ACh)-synthesizing neurons are major components of the enteric nervous system (ENS). They release ACh and peptidergic neurotransmitters onto enteric...
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