Wellness Resources
Epidemiology of osteoporosis.
Osteoporosis is defined as a reduction in bone mass and disruption of bone architecture, resulting in reduced bone strength and...
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Wellness Resources
Osteoclast response to low extracellular sodium and the mechanism of hyponatremia-induced bone loss.
Our recent animal and human studies revealed that chronic hyponatremia is a previously unrecognized cause of osteoporosis that is associated...
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Mild hyponatremia and risk of fracture in the ambulatory elderly.
BACKGROUND: Mild hyponatremia is the commonest electrolyte imbalance in the older population and has been shown to be associated with...
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Sodium homeostasis and bone.
PURPOSE OF REVIEW: Sodium balance is primarily regulated through the renin-angiotensin-aldosterone system. Extracellular fluid (ECF) sodium concentrations ([Na]) reflect the...
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Not Salt But Sugar As Aetiological In Osteoporosis: A Review.
Salt has notoriously been blamed for causing an increase in the urinary excretion of calcium, and thus is a considered...
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Mitochondrial DNA copy number in peripheral blood cells declines with age and is associated with general health among elderly.
The role of the mitochondria in disease, general health and aging has drawn much attention over the years. Several attempts...
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Molecular basis of sun-induced premature skin ageing and retinoid antagonism.
Damage to skin collagen and elastin (extracellular matrix) is the hallmark of long-term exposure to solar ultraviolet irradiation, and is...
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Mitochondrial DNA deletions in human skin reflect photo- rather than chronologic aging.
We have examined the use of mitochondrial DNA (mtDNA) as a molecular marker to study the relation between chronologic aging...
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Reversing wrinkled skin and hair loss in mice by restoring mitochondrial function.
Mitochondrial DNA (mtDNA) depletion is involved in mtDNA depletion syndromes, mitochondrial diseases, aging and aging-associated chronic diseases, and other human...
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