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Adaptation of the cardiac muscle sodium pump to chronic potassium deficiency.

During chronic dietary K+ depletion in rabbits there is a significant reduction of intracellular K+ concentration [( K+]i) in skeletal...

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The Effects of Altered Membrane Cholesterol Levels on Sodium Pump Activity in Subclinical Hypothyroidism.

BACKGROUND:Metabolic dysfunctions characteristic of overt hypothyroidism (OH) start at the early stage of subclinical hypothyroidism (SCH). Na⁺/K⁺-ATPase (the sodium pump)...

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Na,K-ATPase alpha4 isoform is essential for sperm fertility.

Regulation of ion balance in spermatozoa has been shown to be essential for sperm motility and fertility. Control of intracellular...

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An energy budget for signaling in the grey matter of the brain.

Anatomic and physiologic data are used to analyze the energy expenditure on different components of excitatory signaling in the grey...

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The Potassium Channel Odyssey: Mechanisms of Traffic and Membrane Arrangement.

Ion channels are transmembrane proteins that conduct specific ions across biological membranes. Ion channels are present at the onset of...

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Quantitation of [3H]ouabain binding and turnover of Na-K-ATPase along the rabbit nephron.

To determine the number of Na-K-ATPase units and the enzyme's turnover rate along the rabbit nephron, the specific binding of...

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Research reveals the mechanism of the sodium-potassium pump

Researchers have established the structure of a crucial enzyme -- the so-called sodium-potassium pump -- which forms part of every...

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Physiology, Sodium Potassium Pump (Na+ K+ Pump)

The Na+ K+ pump is an electrogenic transmembrane ATPase first discovered in 1957 and situated in the outer plasma membrane...

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Linus Pauling Institute

Potassium Information - Linus Pauling Institute

Maintenance of membrane potentialPotassium is the principal positively charged ion (cation) in the fluid inside of cells, while sodium is...

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