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Developmental exposure to glyphosate-based herbicide and depressive-like behavior in adult offspring: Implication of glutamate excitotoxicity and oxidative stress.

We have previously demonstrated that maternal exposure to glyphosate-based herbicide (GBH) leads to glutamate excitotoxicity in 15-day-old rat hippocampus. The...

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Vitamin C Status Correlates with Markers of Metabolic and Cognitive Health in 50-Year-Olds: Findings of the CHALICE Cohort Study.

A cohort of 50-year-olds from Canterbury, New Zealand (N = 404), representative of midlife adults, undertook comprehensive health and dietary...

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Serum vitamin C and the prevalence of vitamin C deficiency in the United States: 2003-2004 National Health and Nutrition Examination Survey (NHANES).

BACKGROUND:Vitamin C (ascorbic acid) may be the most important water-soluble antioxidant in human plasma. In the third National Health and...

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Plasma Vitamin C Concentrations and Cognitive Function: A Cross-Sectional Study.

Vitamin-C is a water soluble molecule that humans have lost the ability to produce. Vitamin-C plays a role in CNS...

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Maternal vitamin C regulates reprogramming of DNA methylation and germline development.

Development is often assumed to be hardwired in the genome, but several lines of evidence indicate that it is susceptible...

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Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans.

Emerging evidence indicates a central role for the microbiome in immunity. However, causal evidence in humans is sparse. Here, we...

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Blindness Caused by a Junk Food Diet.

Author information1Bristol Eye Hospital, University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom (R.H.).2University Hospitals Bristol NHS Foundation Trust, Bristol,...

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Effect of lifelong carnitine supplementation on plasma and tissue carnitine status, hepatic lipid metabolism and stress signalling pathways and skeletal muscle transcriptome in mice at advanced age.

While strong evidence from clinical studies suggests beneficial effects of carnitine supplementation on metabolic health, serious safety concerns associated with...

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Complementary and Alternative Medicine for Painful Peripheral Neuropathy.

PURPOSE OF REVIEW:The purpose of our manuscript is to review the current evidence supporting the use of complementary and alternative...

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