Wellness Resources
Zearalenone, an estrogenic mycotoxin, is an immunotoxic compound.
The aim of this study was to assess the toxic effects of zearalenone (ZEA) on the immune function. Ovariectomised rats...
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Wellness Resources
Aflatoxins: A Global Concern for Food Safety, Human Health and Their Management.
The aflatoxin producing fungi, Aspergillus spp., are widely spread in nature and have severely contaminated food supplies of humans and...
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Grape Seed Proanthocyanidin Extract Mitigates Titanium Dioxide Nanoparticle (TiO2-NPs)-Induced Hepatotoxicity Through TLR-4/NF-κB Signaling Pathway.
With the progress of nanotechnology, the adverse effects of nanoscale materials are receiving much attention. Inhibition of toll-like receptor 4...
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Radioprotective effect of grape seed extract against gamma irradiation in mouse bone marrow cells.
INTRODUCTION:Ionizing radiations produce free radicals which are often responsible for DNA damage or cell death. Grape seed extract (GSE) is...
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Effect of grape seed extract on maternal toxicity and in utero development in mice treated with zearalenone.
The aims of this study were to determine the polyphone content of grape seed extract (GSE) and to assess their...
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Grape Seed Proanthocyanidin Extract Alleviates AflatoxinB₁-Induced Immunotoxicity and Oxidative Stress via Modulation of NF-κB and Nrf2 Signaling Pathways in Broilers.
Aflatoxin B₁ (AFB₁) is a widely spread mycotoxin contaminates food and feed, causing severe oxidative stress damages and immunotoxicity. Grape...
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Neuroprotective effects of anthocyanin- and proanthocyanidin-rich extracts in cellular models of Parkinson׳s disease.
Neuropathological evidence indicates that dopaminergic cell death in Parkinson׳s disease (PD) involves impairment of mitochondrial complex I, oxidative stress, microglial...
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Dietary proanthocyanidins boost hepatic NAD(+) metabolism and SIRT1 expression and activity in a dose-dependent manner in healthy rats.
Proanthocyanidins (PACs) have been reported to modulate multiple targets by simultaneously controlling many pivotal metabolic pathways in the liver. However,...
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Dietary proanthocyanidins modulate BMAL1 acetylation, Nampt expression and NAD levels in rat liver.
Metabolism follows circadian rhythms, which are driven by peripheral clocks. Clock genes in the liver are entrained by daytime meals...
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