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Methylation deficiency disrupts biological rhythms from bacteria to humans

The methyl cycle is a universal metabolic pathway providing methyl groups for the methylation of nuclei acids and proteins, regulating...

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Social isolation and risk for malnutrition among older people

Aim: Social isolation and loneliness are emerging issues among the geriatric population. The relationships between both, and their impact on...

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Medical empirical research on forest bathing (Shinrin-yoku): a systematic review

Aims: This study focused on the newest evidence of the relationship between forest environmental exposure and human health and assessed...

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Stress, loneliness, and changes in herpesvirus latency

This study used a prospective design to examine the influence of examination stress and loneliness on herpesvirus latency as measured...

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Psychosocial modifiers of immunocompetence in medical students

This study addressed the effects of a naturally occurring stressor on components of the immune response. Blood was drawn twice...

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Social regulation of gene expression in human leukocytes

Background: Social environmental influences on human health are well established in the epidemiology literature, but their functional genomic mechanisms are...

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Social stress up-regulates inflammatory gene expression in the leukocyte transcriptome via β-adrenergic induction of myelopoiesis

Across a variety of adverse life circumstances, such as social isolation and low socioeconomic status, mammalian immune cells have been...

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The neuroendocrinology of social isolation

Social isolation has been recognized as a major risk factor for morbidity and mortality in humans for more than a...

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The role of oxidative stress in cardiovascular disease caused by social isolation and loneliness

Loneliness and social isolation are common sources of chronic stress in modern society. Epidemiological studies have demonstrated that loneliness and...

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