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Vitamin D Deficiency in Children With Vasovagal Syncope Is Associated With Impaired Circadian Rhythm of Blood Pressure.

Background: Vitamin D deficiency is associated with the risk of cardiovascular diseases. We aimed to investigate the serum vitamin D...

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Improvement in Cardiovascular Autonomic Neuropathy After High-Dose Vitamin D Supplementation in Patients With Type 1 Diabetes.

Background: Cardiovascular autonomic neuropathy (CAN) is associated with diabetes mellitus, increasing morbidity and mortality. Some cross-sectional studies associated CAN with...

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Vitamin D in Neurological Diseases: A Rationale for a Pathogenic Impact.

It is widely known that vitamin D receptors have been found in neurons and glial cells, and their highest expression...

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Nutritional Strategies to Modulate Intracellular and Extracellular Buffering Capacity During High-Intensity Exercise.

Intramuscular acidosis is a contributing factor to fatigue during high-intensity exercise. Many nutritional strategies aiming to increase intra- and extracellular...

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Carnosine protects cardiac myocytes against lipid peroxidation products.

Endogenous histidyl dipeptides such as carnosine (β-alanine-L-histidine) form conjugates with lipid peroxidation products such as 4-hydroxy-trans-2-nonenal (HNE and acrolein), chelate...

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Hyaluronan-carnosine conjugates inhibit Aβ aggregation and toxicity.

Alzheimer's disease is the most common neurodegenerative disorder. Finding a pharmacological approach that cures and/or prevents the onset of this...

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Carnosine quenches the reactive carbonyl acrolein in the central nervous system and attenuates autoimmune neuroinflammation.

Background: Multiple sclerosis (MS) is a chronic autoimmune disease driven by sustained inflammation in the central nervous system. One of...

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Carnosine Prevents Different Structural Damages Induced by Methylglyoxal in Lens Crystallins.

The elevated lenticular level of methylglyoxal (MGO) in diabetic patients is an important risk factor for the development of age-related...

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Physiology and pathophysiology of carnosine.

Carnosine (β-alanyl-l-histidine) was discovered in 1900 as an abundant non-protein nitrogen-containing compound of meat. The dipeptide is not only found...

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