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Impact of the Local Inflammatory Environment on Mucosal Vitamin D Metabolism and Signaling in Chronic Inflammatory Lung Diseases.

Vitamin D plays an active role in the modulation of innate and adaptive immune responses as well as in the...

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Mucosal vitamin D signaling in inflammatory bowel disease.

Epidemiological studies have identified vitamin D (25(OH)D) deficiency to be highly prevalent among patients with inflammatory bowel disease (IBD), and...

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A Review of Topical and Systemic Vitamin Supplementation in Ocular Surface Diseases.

In the homeostasis of the ocular surface, vitamins play a critical role in regulating inflammatory responses and promoting cell differentiation,...

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Vitamin A, infection, and immune function.

In populations where vitamin A availability from food is low, infectious diseases can precipitate vitamin A deficiency by decreasing intake,...

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Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection.

Obesity, diabetes, and related manifestations are associated with an enhanced, but poorly understood, risk for mucosal infection and systemic inflammation....

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Gastric barrier function and toxic damage.

Gastric epithelium is the first significant barrier between the inner body and the potentially toxic material in the lumen. Nutrients...

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Diet-Microbe-Host Interactions That Affect Gut Mucosal Integrity and Infection Resistance.

The gastrointestinal tract microbiome plays a critical role in regulating host innate and adaptive immune responses against pathogenic bacteria. Disease...

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Leaky gut: mechanisms, measurement and clinical implications in humans

The objectives of this review on 'leaky gut' for clinicians are to discuss the components of the intestinal barrier, the...

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Negative Effects of a High-Fat Diet on Intestinal Permeability: A Review.

The intestinal tract is the largest barrier between a person and the environment. In this role, the intestinal tract is...

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