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Study Title:

Pantethine Supports Natural Stress Response

Study Abstract

Study of the corticosteroid content in the adrenals and blood of rats under pantothenate deficiency has demonstrated a decrease in adrenocortical function. A single administration of pantothenate in a dose of 3.3 mg/kg reduced the influence of hypovitaminosis on the adrenals. The pantothenate derivatives (pantethine, 4'-phosphopantothenate and CoA in particular) injected to intact animals in a single dose equimolar to 3.3 mg/kg calcium pantothenate per kg bw had a marked steroidogenous effect.

Study Information

Tarasov IuA, Sheibak VM, Moiseenok AG.
Adrenal cortex functional activity in pantothenate deficiency and the administration of the vitamin or its derivatives.
Vopr Pitan.
1985 July
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