Fisetin

Longevity and Cognitive Support*

16 total reviews

Fisetin is a nootropic or smart nutrient that supports mental sharpness, creativity, motivation, and cognitive function. It is a potent senolytic compound and Sirt1 activator for cellular health and longevity.*

40% off! Best by date December 2026

Size: 100mg, 90caps

In Stock - Ships Same or Next Day

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  • Manufactured in USA & Third-Party Tested


Give your brain a boost!*

  • Nootropic nutrient for focus and mental sharpness*
  • Senolytic compound that helps clear senescent cells*
  • Promotes healthy cellular aging and longevity*
  • Boosts memory, focus, and learning*
  • Safely and naturally supports cognitive function*
  • Branded Novusetin® Fisetin shows many positive health benefits in research

How It Works

Wellness Resources Fisetin contains a branded extract of the flavonoid fisetin, called Novusetin. Fisetin is an antioxidant nutrient that has demonstrated a high level of nerve and brain protection along with boosting memory and new nerve cell growth. It has been shown to enhance the gene function of nerve cells involved with memory.*

  • Natural nootropic, enhances brain function*
  • Senolytic agent, supports cellular metabolism and longevity*
  • Sirtuin activating compound*
  • Helps focus, memory, and concentration*
  • 100mg Novusetin Fisetin, 90 capsules per bottle - excellent value!
  • Helps build the core antioxidant system within cells, known as glutathione*

Longevity

Fisetin shows great promise as a longevity support nutrient.  It is one of natures most potent senolytics.  Senolytic compounds support the body's process of clearing senescent cells.  Senescent cells are aging cells that no longer function correctly, and have lost their ability to divide. Fisetin is a sirtuin activating compound (SATC). Sirtuins are a family of compounds that promote cellular metabolism and DNA repair.*

Antioxidant

Fisetin is a dietary flavonoid found in various fruits (strawberries, apples, mangoes, persimmons, kiwis, and grapes) and vegetables (tomatoes, onions, and cucumbers). Strawberries have the highest amount of any food. You would need to eat a pound of strawberries to get 73mg of fisetin.*

Natural Nootropic

Fisetin is considered a natural nootropic. Nootropics are compounds that enhance brain function. Fisetin supplements offer a way to safely and naturally support brain health and focus.*

Novusetin® Fisetin

Wellness Resources Fisetin is a branded fisetin raw material called Novusetin®, sourced from the Japanese fruit wax tree (Rhus succedanea). It is a naturally derived fisetin flavonoid nutrient known to support cognitive health. Novusetin® is highly researched and has been issued a patent for enhancing memory.*

100mg Capsules, 90-Day Supply

Wellness Resources Fisetin capsules provide 100mg of pure Novusetin® Fisetin per capsule with 90 vegetarian capsules per bottle. It is the best value for a superior quality Fisetin supplement!

Wellness Resources - Since 1985

Wellness Resources formulates 90+ superior quality supplements that deliver the most absorbable nutrients in optimal amounts to make a true difference in your health.

Family-Owned Since 1985

We care about your health! As a family-owned company founded in 1985, we are committed to formulating the very best nutritional supplements for health results!

Manufactured in the United States

Wellness Resources supplements are manufactured in the USA in labs that follow GMP (good manufacturing practice) guidelines to ensure quality and potency.

  • Every lot tested for product quality, purity, potency
  • Third party testing to verify you are getting exactly what's on the label
  • Tested for contaminants such as heavy metals and microbes
  • FDA registered labs

You are getting the highest purity supplements on the market!

Transparency in Labeling

Wellness Resources supplements are formulated with the highest purity, most absorbable raw material nutrients. We use the same forms of nutrients used in research – nutrients that are proven to be well absorbed and used by the body. We list the exact nutrient forms and amounts on the label!

How To Take

Take 1 capsule per day.

Fisetin

Directions:

Take 1 capsule per day.

Supplement Facts

Serving Size:

1 capsule

Amount Per Serving % Daily Value
Novusetin® Fisetin (Rhus succedanea) (stem) 100 mg *

* Daily Value not established

Other Ingredients: cellulose capsule, cellulose, and rice hulls.

This product does NOT contain: milk, egg, fish, Crustacean shellfish, tree nuts, peanuts, wheat, gluten, soy, or sesame. This product does not contain hidden fillers, preservatives, sugar, artificial sweeteners, colors, or flavors.

Novusetin® is a registered trademark of Omega Protein Corporation, d/b/a Nutegrity.

Manufactured in the USA

We source the highest quality, most absorbable nutrients. Our supplements are manufactured in the United States under stringent quality standards.

Third-Party Tested

Wellness Resources supplements are tested throughout production for potency and purity. Each final batch is tested to ensure you are getting what's on the label.

Family-Owned Since 1985

Our specialty formulas are backed by science and years of experience. Made with care, from our family to yours. A supplement line you can trust.

Customers praised this brain health supplement for improving memory, focus, and mental clarity. Many reported "really made a difference" after long-term use. Benefits noted include cognitive enhancement, feeling youthful, and unexpected muscle fitness improvements. Some found it hard to assess effectiveness early on. Valued for competitive pricing and no questionable fillers.

  • 5 stars: 11 (69%)
  • 4 stars: 3 (19%)
  • 3 stars: 1 (6%)
  • 2 stars: 1 (6%)
  • 1 star: 0 (0%)
A
Aestickley

I have been taking this as part of my brain health supplement daily routine for several years and believe it has significantly helped improve my memory and focus. Take along with Brain Booster and PhosphatidlySerine

L
Linda Belk

Take once a day to keep my mind clear. I have taken this for a year now and can really tell the difference.

T
Timothy Woods

too early to tell

B
Brian Dravis
Good Price for Fisetin

Great Price for Fisetin and prompt delivery as always.

M
MacKenzie
Fisetin

I've been taking Fisetin for over a year and I feel that it keeps me feeling youthful.

A
ABasinHowdy
Good Product

Packaged well, Great Value, Shipped fast. Though, of course, I will not know for years, and I may never know, if this product helps me. But research says it might.

N
Nancy T. Wrede
Fisetin for brain health!

I have been reading about Fisetin and was excited to find the product for sale at a reasonable price. I am taking it in hopes of it improving my brain health!

M
Mary A. Showalter
Cognitive benefits

This stuff is the bomb. I read about it in a book and decided to try it. It has REALLY made a difference in my memory. Try it - I promise you will not be sorry!!

S
Sunshine and smiles
yum! Cell replacement here I come

I don't know if its working. How could I? They are easy to swallow and have a slight ordor, but the science behind Fisetin is rather good.

C
Carol aka CJ
I think this is helping me.

I have only taken this product for a month not sure if my cognitive capabilities have improved although I feel more alert.

N
Nikolay
Best price on the market

I was tired of Doctor's Best empty bottle with just 30 small pills, and this one is more environmentally-friendly and also more economical with no questionable fillers! I only wish it participated in the Subscribe & Save program!Edit: It's now available in the Subscribe & Save program!

D
Dean Gordon
They are ok I guess

I honestly cannot tell if these are doing anything for me. I purposely got a low dose to start with but when I take two I still cannot tell a difference in anything for which I purchased them.

S
S. Murphy
wellbeing

I started taking Fisetin and my chronic bursitis is as good as gone, I haven't had a flare up in months I also got very lite and short colds during this winter, I feel that this product really helped boost my immune system

K
Kdssant22
Yay

I love this product

A
Alonso's Ghost
Effective in unexpected way

I first tried Fisetin in 2018. As I’ve gotten older, maintaining muscle fitness has become more difficult. This chemical appears to change something as I have been able to rebuild muscle strength, tone and mass as well as I did 20 years earlier. I suspect it does something for cellular metabolism like a tuneup. It seems to last about a year before wearing off. Then I repeat the treatment. 500 mg a day for 4 days then again in 2 weeks works for me.

A
Amazon Customer
Great product. Great price. It works.

I was skeptical at first, but have taken it for 6 months now. I definitely notice a change for the better...more focus, more clarity & able to remember more things. I am a 69 yr old female & was really struggling with focus & remembering small things. Since beginning taking this my friends & co-workers have noticed an improvement.