Resveratrol is a nutrient known to activate a potent gene signal called SIRT1. SIRT1 first drew attention as the primary gene signal involved with the longevity benefits of calorie restriction. A very simple explanation is that when you are in a food scarcity situation, SIRT1 is activated to help break down your stored fat to use as fuel as well as boost your energy so that you have enough energy to hunt for new food. SIRT1 is part of a famine related survival system.

It is important to understand that just about everyone who is overweight and having trouble with cravings has high leptin in their blood (leptin resistance), and that ...