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When your adrenal glands have been working too hard for too long they simply may not be able to keep up. Sometimes this is triggered by emotional loss, physical pain, or simply prolonged stress. Things just start feeling too out-of-control or overwhelming.
Your adrenals are the foundation for your entire ability to adapt to anything. This system talks to other systems, such as your subconscious brain (the HPA axis hypothalamus-pituitary-adrenals). There is another communication loop that goes between your adrenals, thymus gland (emotions-sadness), and serotonin nerves (right brain-state of mood).
The out-of-control feeling ...