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A paradigm shift for the prevention and treatment of individual and global obesity.

The prevalence of obesity and overweight has plateaued in developed countries, although at high levels, but in most parts of...

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Implication of neurohormonal-coupled mechanisms of gastric emptying and pancreatic secretory function in diabetic gastroparesis.

Recently, diabetic gastroparesis (DGP) has received much attention as its prevalence is increasing in a dramatic fashion and management of...

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Redefining the functional roles of the gastrointestinal migrating motor complex and motilin in small bacterial overgrowth and hunger signaling.

During the fasting state the upper gastrointestinal tract exhibits a specific periodic migrating contraction pattern that is known as the...

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Dysmotility and proton pump inhibitor use are independent risk factors for small intestinal bacterial and/or fungal overgrowth.

BACKGROUND: Whether intestinal dysmotility and the use of a proton pump inhibitor (PPI) either independently or together contributes to small...

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Gastro-oesophageal reflux and the migrating motor complex.

Distal oesophageal pH and gastroduodenal motor activity were recorded simultaneously throughout nocturnal (23 30-08 30 h) and diurnal (08 30-17...

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Underlying mechanism of the cyclic migrating motor complex in Suncus murinus: a change in gastrointestinal pH is the key regulator.

In the fasted gastrointestinal (GI) tract, a characteristic cyclical rhythmic migrating motor complex (MMC) occurs in an ultradian rhythm, at...

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Motilin-induced gastric contractions signal hunger in man.

RATIONALE: Hunger is controlled by the brain, which receives input from signals of the GI tract (GIT). During fasting, GIT...

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The Migrating Motor Complex

The migrating motor complex is a distinct pattern of electromechanical activity observed in gastrointestinal smooth muscle during the periods between...

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Importance of the enteric nervous system in the control of the migrating motility complex.

The migrating motility complex (MMC), a cyclical phenomenon, represents rudimentary motility pattern in the gastrointestinal tract. The MMC is observed...

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