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Dietary implications for patients receiving long-term oral anticoagulation therapy for treatment and prevention of thromboembolic disease.

The effectiveness of oral anticoagulation therapy with warfarin (a vitamin K antagonist) in the treatment of thromboembolic disease, including stroke...

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Warfarin and vitamin K intake in the era of pharmacogenetics.

The considerable variability in the warfarin dose-response relationship between individuals, is explained mainly by genetic variation in its major metabolic...

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Vitamin K: a practical guide to the dietary management of patients on warfarin.

Warfarin has been successfully used in the medical management of thromboembolic disease for nearly six decades. It is widely assumed...

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Avoidance of Vitamin K-Rich Foods Is Common among Warfarin Users and Translates into Lower Usual Vitamin K Intakes.

BACKGROUND:Warfarin users should aim for stable daily vitamin K intakes. However, some studies report that patients are often advised to...

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Statins stimulate atherosclerosis and heart failure: pharmacological mechanisms.

In contrast to the current belief that cholesterol reduction with statins decreases atherosclerosis, we present a perspective that statins may...

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The Relationships Between Vitamin K and Cognition: A Review of Current Evidence.

Vitamin K is a fat-soluble nutrient discovered in 1935 and its role in blood coagulation has been thoroughly explored. In...

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Vitamin K status and cognitive function in healthy older adults.

Evidence is accumulating that vitamin K could have a role in cognition, especially in aging. Using data from the Québec...

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Desphospho-uncarboxylated matrix Gla protein is a novel circulating biomarker predicting deterioration of renal function in the general population.

BACKGROUND:Recent studies showing an inverse association between estimated glomerular filtration rate (eGFR), a microvascular trait, and inactive desphospho-uncarboxylated matrix Gla...

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Vitamin K2 is a mitochondrial electron carrier that rescues pink1 deficiency.

Human UBIAD1 localizes to mitochondria and converts vitamin K(1) to vitamin K(2). Vitamin K(2) is best known as a cofactor...

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