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Risk of irritable bowel syndrome in patients who underwent appendectomy: A nationwide population-based cohort study.

AbstractBackground: Appendectomy is one of the most common surgical procedures; however, the possible long-term consequences have not been fully explored....

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Quercetin attenuates oxidative stress-induced apoptosis via SIRT1/AMPK-mediated inhibition of ER stress in rat chondrocytes and prevents the progression of osteoarthritis in a rat model

Apoptosis of chondrocytes are the main initiator of osteoarthritis (OA) and can be explained by oxidative stress and endoplasmic reticulum...

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Quercetin and the mitochondria: A mechanistic view

Quercetin is an important flavonoid that is ubiquitously present in the diet in a variety of fruits and vegetables. It...

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Actions of Quercetin, a Polyphenol, on Blood Pressure

Disorder of blood pressure control causes serious diseases in the cardiovascular system. This review focuses on the anti-hypertensive action of...

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Mechanistic Aspects and Therapeutic Potential of Quercetin against COVID-19-Associated Acute Kidney Injury

The inflammatory mediator and oxidant agent storm caused by the SARS-CoV-2 infection has been strongly associated with the failure of...

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The Antidiabetic Potential of Quercetin: Underlying Mechanisms

The dramatic increase in modern lifestyle diseases such as cancer, cardiovascular diseases and diabetes has renewed researchers' interest to explore...

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Quercetin-Induced Cell Death in Human Papillary Thyroid Cancer (B-CPAP) Cells

In this study, we have investigated the antiproliferative effect of quercetin on human papillary thyroid cancer cells and determined the...

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Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More

Increasing interest has recently focused on determining whether several natural compounds, collectively referred to as nutraceuticals, may exert neuroprotective actions...

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Nrf2

NF-E2–related factor 2 (Nrf2) is an essential transcription factor that regulates an array of detoxifying and antioxidant defense gene expression...

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