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Impact of Cholesterol Metabolism in Immune Cell Function and Atherosclerosis.

Cholesterol, the most important sterol in mammals, helps maintain plasma membrane fluidity and is a precursor of bile acids, oxysterols,...

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The Intracellular Cholesterol Landscape: Dynamic Integrator of the Immune Response.

Cholesterol has typically been considered an exogenous, disease-related factor in immunity; however, recent literature suggests that a paradigm shift is...

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Cholesterol Review: A Metabolically Important Molecule.

Objective: Cholesterol is an important molecule in humans and both its excess and its deficiency cause disease. Most clinicians appreciate...

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Sphingolipid/cholesterol regulation of neurotransmitter receptor conformation and function.

Like all other monomeric or multimeric transmembrane proteins, receptors for neurotransmitters are surrounded by a shell of lipids which form...

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Myelin Fat Facts: An Overview of Lipids and Fatty Acid Metabolism.

Myelin is critical for the proper function of the nervous system and one of the most complex cell-cell interactions of...

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Brain cholesterol: long secret life behind a barrier.

Although an immense knowledge has accumulated concerning regulation of cholesterol homeostasis in the body, this does not include the brain,...

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Transporters for the Intestinal Absorption of Cholesterol, Vitamin E, and Vitamin K.

Humans cannot synthesize fat-soluble vitamins such as vitamin E and vitamin K. For this reason, they must be obtained from...

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Cholesterol: Sources, Absorption, Function, and Metabolism

Regulation of Cholesterol SynthesisRegulation of cholesterol synthesis can be explained in simple economic terms. As with every efficient economy, the...

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Potential Developmental and Reproductive Impacts of Triclocarban: A Scoping Review.

Triclocarban (TCC) is an antimicrobial agent used in personal care products. Although frequently studied with another antimicrobial, triclosan, it is...

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