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Experimental and clinical reports on anti-inflammatory, antioxidant, and immunomodulatory effects of Curcuma longa and curcumin, an updated and comprehensive review.

Curcuma longa (C. longa) or turmeric is a plant with a long history of use in traditional medicine, especially for...

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Effects of Curcumin on Microglial Cells.

Microglia are innate immune system cells which reside in the central nervous system (CNS). Resting microglia regulate the homeostasis of...

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Effects of curcumin on mitochondria in neurodegenerative diseases.

Neurodegenerative diseases (NDs) result from progressive deterioration of selectively susceptible neuron populations in different central nervous system (CNS) regions. NDs...

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Curcumin for depression: a meta-analysis.

Curcumin is the principal curcuminoid found in turmeric (Curcuma longa), a spice frequently used in Asian countries. Given its anti-inflammatory...

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Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.

Although turmeric and its curcumin-enriched extracts have been used for treating arthritis, no systematic review and meta-analysis of randomized clinical...

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Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis.

Objective: To investigate the efficacy and safety of dietary supplements for patients with osteoarthritis.Design: An intervention systematic review with random...

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Curcumin, a Multifaceted Hormetic Agent, Mediates an Intricate Crosstalk between Mitochondrial Turnover, Autophagy, and Apoptosis.

Curcumin has extensive therapeutic potential because of its antioxidant, anti-inflammatory, and antiproliferative properties. Multiple preclinical studies in vitro and in...

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Mitochondria as a target in the therapeutic properties of curcumin.

Curcumin, a phenolic compound extracted from Curcuma longa, is commonly used in Asia as a spice and pigment and has...

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Research on curcumin: A meta-analysis of potentially malignant disorders.

Introduction: Turmeric has been described in ayurveda, and is referred by different names in different cultures, the active principle called...

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