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The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria.

Brown and beige adipocytes are specialized cells that express uncoupling protein 1 (UCP1) and dissipate chemical energy as heat. These...

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Beige Fat Maintenance; Toward a Sustained Metabolic Health.

Understanding the mammalian energy balance can pave the way for future therapeutics that enhance energy expenditure as an anti-obesity and...

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White adipose tissue mitochondrial metabolism in health and in obesity.

White adipose tissue is one of the largest organs of the body. It plays a key role in whole-body energy...

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Brown and Beige Adipose Tissues in Health and Disease.

Brown and beige adipocytes arise from distinct developmental origins. Brown adipose tissue (BAT) develops embryonically from precursors that also give...

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The Role of Exercise, Diet, and Cytokines in Preventing Obesity and Improving Adipose Tissue.

The prevalence of obesity continues to rise worldwide despite evidence-based public health recommendations. The promise to adopt a healthy lifestyle...

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Role of Choline in Ocular Diseases.

Choline is essential for maintaining the structure and function of cells in humans. Choline plays an important role in eye...

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Interaction of alpha-crystallin with four major phospholipids of eye lens membranes.

It is well-studied that the significant factor in cataract formation is the association of α-crystallin, a major eye lens protein,...

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Enhanced depletion of lens reduced glutathione Adriamycin in riboflavin-deficient rats.

The anticancer drug Adriamycin has photosensitizing properties which potentially may be detrimental to lens tissue. Since reduced glutathione (GSH) serves...

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Eye lens in aging and diabetes: effect of quercetin.

Old age is accompanied by a number of pathological eye conditions. Cataract is the most common age-related eye complication. Because...

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