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Hypoglycemia, brain energetics, and hypoglycemic neuronal death.

Hypoglycemia is a common and serious problem among diabetic patients receiving treatment with insulin or other glucose-lowering drugs. Moderate hypoglycemia...

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Glutamate and Mitochondria: Two Prominent Players in the Oxidative Stress-Induced Neurodegeneration.

The aetiology of major neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD) is still unknown, but increasing...

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Glutamate receptors, neurotoxicity and neurodegeneration.

Glutamate excitotoxicity is a hypothesis that states excessive glutamate causes neuronal dysfunction and degeneration. As glutamate is a major excitatory...

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Increased oxidative stress, inflammation, and glutamate: Potential preventive and therapeutic targets for hearing disorders.

Hearing disorders constitute one of the major health concerns in the USA. Decades of basic and clinical studies have identified...

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Inflammation, Glutamate, and Glia: A Trio of Trouble in Mood Disorders.

Increasing data indicate that inflammation and alterations in glutamate neurotransmission are two novel pathways to pathophysiology in mood disorders. The...

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Glutamate and depression: Reflecting a deepening knowledge of the gut and brain effects of a ubiquitous molecule.

The versatility of glutamate as the brain's foremost excitatory neurotransmitter and modulator of neurotransmission and function is considered common knowledge....

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Glutamate: a truly functional amino acid.

Glutamate is one of the most abundant of the amino acids. In addition to its role in protein structure, it...

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A neuro-metabolic account of why daylong cognitive work alters the control of economic decisions.

Behavioral activities that require control over automatic routines typically feel effortful and result in cognitive fatigue. Beyond subjective report, cognitive...

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Dietary magnesium deficiency alters gut microbiota and leads to depressive-like behaviour.

Objective: Gut microbiota (GM) has previously been associated with alterations in rodent behaviour, and since the GM is affected by...

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