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Tocotrienols for Brain Health

Vitamin E is essential for normal neurological function. It is the major lipid-soluble, chain-breaking antioxidant in the body, protecting the...

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Tocotrienols Work In Part by Modulating NF-kappaB

Unlike the tocopherols, the tocotrienols, also members of the vitamin E family, have an unsaturated isoprenoid side chain. In contrast...

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Tocotrienols Modulate NF-kappaB-Driven Circulatory Stress

Alpha-tocopherol and its esterified derivatives have been shown to be effective in reducing monocytic-endothelial cell adhesion. However, the effect of...

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Strategies for new Vaccines

Vaccination is well known to control many current infectious diseases. However, the development of cellular (Th1) immunity to control viral...

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Manipulating NF-kappaB is Crucial in Better Vaccine Development

There is a pressing need for adjuvants that will enhance the effectiveness of genetic vaccines. This is particularly important in...

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Aluminum Vaccine Adjuvant Linked to Chronic Fatigue and Pain

Macrophagic myofasciitis is a condition first reported in 1998, which cause remained obscure until 2001. Over 200 definite cases have...

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Adjuvants Pose Significant Toxicity Problem

Adjuvants, substances included in many vaccines in order to improve immune responses, are challenging to develop and license because adjuvant...

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Aluminum Vaccine Adjuvant is Nerve Toxic

Gulf War illness (GWI) affects a significant percentage of veterans of the 1991 conflict, but its origin remains unknown. Associated...

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Brain Protection Against Methylmercury from Tocotrienols

Excessive free radical formation has been implicated as one of the causative factors in neurotoxic damage associated with variety of...

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