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Leptin, the Arousal Thermostat, and Sleep Disordered Breathing

OBJECTIVE: The purpose of this work was to determine whether, in children with metabolic syndrome and sleep-disordered breathing, metabolic markers...

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Sleep Apnea Raises Blood Pressure in Children

BACKGROUND: Childhood obstructive sleep apnoea (OSA) is increasingly being recognised. Its effects on blood pressure (BP) elevation and hypertension are...

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An Arousal Thermostat that Influences Sleep and Addiction

Association between sleep disturbances and hormonal imbalances can result in metabolic disorders, including obesity and diabetes. The hypothalamus is likely...

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Teen Sleep Problems, Depression, and Substance Abuse

Study Objective: To evaluate the association between adolescent insomnia and mental health during adolescence and young adulthood. Design: Cross-sectional and...

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Sleep and Cognitive Trouble in Children

Rationale: An association between neurocognitive deficits and pediatric sleep-disordered breathing has been suggested; however, weak correlations between disease severity and...

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Lack of Sleep Raises Blood Pressure in Teens

Background—We assessed whether insufficient sleep is associated with prehypertension in healthy adolescents.Methods and Results—We undertook a cross-sectional analysis of 238...

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Mild Sleep Problems Cause Circulatory Inflammation

Rationale: Moderate–severe obstructive sleep apnea (OSA) is associated with endothelial dysfunction, increased arterial stiffness, and hypertension. It is not known...

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Sleep Problems and the Risk of Early Death

BACKGROUND: Sleep-disordered breathing (SDB) is a treatable but markedly under-diagnosed condition of frequent breathing pauses during sleep. SDB is linked...

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Sleep Loss and Inflammation

BackgroundAccumulating evidence suggests that sleep disturbance is associated with inflammation and related disorders including cardiovascular disease, arthritis, and diabetes mellitus....

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